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Guyton and Hall Textbook of Medical Physiology (Guyton Physiology) | 15th Edition
by John E. Hall PhD (Author), Michael E. Hall MD MSc. (Author)
A favorite text of physiology students worldwide, Guyton and Hall Textbook of Medical Physiology delivers the complex knowledge you need to master in a distinctive, easy-to-digest format. The fifteenth Edition of this bestselling text is fully up to date and provides clear, comprehensive coverage of the content most relevant to clinical and pre-clinical students. The unique format ensures maximum learning and retention of complex concepts: a larger font size emphasizes core information, while supporting information is detailed in a smaller font and highlighted in pale blue―making it easy to quickly skim the essential text or pursue more in-depth study.
- Focuses on core material and how the body maintains homeostasis to remain healthy, emphasizing the important principles that will aid in later clinical decision making
- Contains new information on physiology and the gut microbiome and clinically important sex differences in physiology lab values
- Presents information in short chapters using a concise, readable voice that facilitates learning and retention
- Utilizes two font sizes: a larger font for fundamentals, and a smaller font that highlights relevant integrated sciences, clinical examples, pathophysiology, or detailed mechanisms that students can read as needed
- Contains more than 1,200 full-color drawings and diagrams―all carefully crafted to make physiology easier to understand
- Includes online access to heart sounds, animations, self-assessment questions,
Table Of Contents :
UNIT I: Introduction to Physiology: The Cell and General Physiology
1. Functional Organization of the Human Body and Control of the “Internal Environment”
Cells Are the Living Units of the Body
Extracellular Fluid—The “Internal Environment”
Homeostasis—Maintenance of a Stable Internal Environment
Control Systems of the Body
Physiological Variability
2. The Cell and Its Functions
Organization of the Cell
Cell Structure
Functional Systems of the Cell
Locomotion of Cells
3. Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction
Cell Nucleus Genes Control Protein Synthesis
Transcription—Transfer of Cell Nucleus DNA Code to Cytoplasm RNA Code
Translation—Formation of Proteins on the Ribosomes
Protein Enzymes Control Synthesis of Other Substances in the Cell
Regulation of Gene Function and Biochemical Activity in Cells
The DNA–Genetic System Controls Cell Reproduction
Cell Differentiation
Apoptosis—Programmed Cell Death
Cancer
UNIT II: Membrane Physiology, Nerve, and Muscle
4. Transport of Substances Through Cell Membranes
The Cell Membrane Is a Lipid Bilayer With Cell Membrane Transport Proteins
Diffusion
Active Transport of Substances Through Membranes
5. Membrane Potentials and Action Potentials
Basic Physics of Membrane Potentials
Resting Membrane Potential of Neurons
Neuron Action Potential
Propagation of the Action Potential
Importance of Energy Metabolism for Reestablishing Sodium and Potassium Ionic Gradients After Action Potentials Are Completed
Plateau in Some Action Potentials
Rhythmicity of Some Excitable Tissues—Repetitive Discharge
Special Characteristics of Signal Transmission in Nerve Trunks
Excitation—The Process of Eliciting the Action Potential
6. Contraction of Skeletal Muscle
Physiological Anatomy of Skeletal Muscle
General Mechanism of Muscle Contraction
Molecular Mechanisms of Muscle Contraction
Energetics of Muscle Contraction
Characteristics of Whole Muscle Contraction
7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling
Neuromuscular Junction and Transmission of Impulses From Nerve Endings to Skeletal Muscle Fibers
Muscle Action Potential
Excitation-Contraction Coupling
8. Excitation and Contraction of Smooth Muscle
Contraction of Smooth Muscle
Regulation of Contraction By Calcium Ions
Nervous and Hormonal Control of Smooth Muscle Contraction
UNIT III: The Heart
9. Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves
Cardiac Muscle Physiology
The Cardiac Cycle
Regulation of Heart Pumping
10. Rhythmical Excitation of the Heart
Specialized Excitatory and Conductive System of the Heart
Control of Excitation and Conduction in the Heart
11. Fundamentals of Electrocardiography
Waveforms of the Normal Electrocardiogram
Flow of Current Around the Heart During the Cardiac Cycle
Electrocardiographic Leads
12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis
Vectorial Analysis of Electrocardiograms
Vectorial Analysis of the Normal Electrocardiogram
Mean Electrical Axis of the Ventricular QRS and Its Significance
Con